advanced glycation end-products


advanced glycation end-products
damaged proteins that result from the glycation of a large number of body proteins, which can accumulate and cause permanent damage to tissues. This damage is more prevalent in diabetics due to chronic exposure to blood with high concentrations of glucose. It is believed to be partly responsible for the damage to the kidneys, eyes, and blood vessels that characterizes long-standing diabetes.

The new mediacal dictionary. 2014.

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  • advanced glycation end products — (AGE) irreversible products of the glycation of proteins, which cause tissue damage; seen when blood glucose concentrations are chronically elevated such as in diabetes mellitus, arthritis, and aging …   Medical dictionary

  • advanced glycation end-products — damaged proteins that result from the glycation of a large number of body proteins, which can accumulate and cause permanent damage to tissues. This damage is more prevalent in diabetics due to chronic exposure to blood with high concentrations… …   Medical dictionary

  • Advanced glycation end product — Advanced Glycation End products (AGEs) are the result of a chain of chemical reactions after an initial glycation reaction. The intermediate products are known, variously, as Amadori, Schiff base and Maillard products, named after the researchers …   Wikipedia

  • Glycation — (sometimes called non enzymatic glycosylation) is the result of the bonding of a protein or lipid molecule with a sugar molecule, such as fructose or glucose, without the controlling action of an enzyme. All blood sugars are reducing molecules.… …   Wikipedia

  • Glycation — La réaction de Maillard, connue dans le monde médical sous le nom de « glycation non enzymatique des protéines », a d’abord été étudiée dans le cadre du diabète sucré grâce à l’hémoglobine glyquée. La glycation est une réaction… …   Wikipédia en Français

  • glycation — The nonenzymic reaction that forms a glycate. * * * n. the chemical linkage of glucose to a protein, to form a glycoprotein. Glycation of body proteins has been postulated as a cause of complications of diabetes mellitus. See advanced… …   Medical dictionary

  • glycation — n. the chemical linkage of glucose to a protein, to form a glycoprotein. Glycation of body proteins has been postulated as a cause of complications of diabetes mellitus. See: advanced glycation end products, glycated haemoglobin …   The new mediacal dictionary

  • Raw foodism — Articleissues|cleanup=September 2008|refimprove=March 2008| self published = September 2008Raw foodism (or rawism) is a lifestyle promoting the consumption of un cooked, un processed, and often organic foods as a large percentage of the diet. If… …   Wikipedia

  • 3-Deoxyglucosone — IUPAC name (4S,5R) 4,5,6 Trihydroxy 2 oxohexanal …   Wikipedia

  • Diabetic foot ulcer — is one of the major complications of diabetes mellitus, and probably the major component of the diabetic foot. It occurs in 15% of all patients with diabetes and precedes 84% of all lower leg amputations.[1] Major increase in mortality among… …   Wikipedia


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